Clinical specialists with Perfusion Solution work to perfuse donor lungs using XVIVO’s XPS™ Ex Vivo Lung Perfusion (EVLP) platform before the lungs are reassessed for a potential lifesaving transplant surgery. Photo courtesy Perfusion Solution.
New technology utilizes mechanical perfusion to make marginal lung donation viable for January 2026 lifesaving transplant
On Jan. 29, 2026, an Indiana man’s donated lungs were recovered for potential transplant but were rejected by several regional transplant centers due to their marginal performance.
Indiana Donor Network partnered with Sweden-based XVIVO and Wisconsin-based Perfusion Solution to reassess the lungs, mechanically perfuse them and improve their functionality.
The result: After 5 hours undergoing mechanical perfusion, the donor lungs were accepted for transplant and saved an Indiana man’s life the same day.
Indiana Donor Network became the first organ recovery organization in the U.S. to establish an in-house lung perfusion system to increase the vibrancy of lungs for future lifesaving transplantations.
Indiana Donor Network is the first organ recovery organization in the U.S. to utilize an in-house machine perfusion system that keeps donated lungs functional outside the human body and helps reassess the viability of marginally performing lungs for transplantation.
A new partnership between Indiana Donor Network, global medtech company XVIVO, headquartered in Sweden, and Beloit, Wisconsin-based Perfusion Solution is now being utilized by Indiana Donor Network clinical teams to better serve regional transplant centers and partner hospitals involved in lung recovery and transplantation.
“Advancements in technology are transforming organ transplantation at every stage – from the recovery of a donated organ to the moment it gives someone a second chance at life,” said Indiana Donor Network Director of Organ Services Sherry Quire. “Saving lives involves more than the successful recovery of a generous gift. We are committed to preserving and enhancing organ vitality outside the body so each transplant has the greatest possible opportunity to succeed.”
Sherry Quire
Director, Organ Services
Indiana Donor Network
The system – involving the utilization of XVIVO’s XPS™ Ex Vivo Lung Perfusion (EVLP) platform, perfusion specialists and equipment of Perfusion Solution, and the clinical organ recovery staff of Indiana Donor Network – was initially implemented Jan. 29.
XVIVO’s XPS™ Ex Vivo Lung Perfusion (EVLP) platform. Photo courtesy of XVIVO.
From recovery through perfusion to lifesaving transplant in 1 day
That day, an Indiana man hospitalized at a northeastern Indiana hospital died. The registered organ donor’s lungs were recovered then transferred to Indiana Donor Network Organ and Tissue Recovery Center in Indianapolis for clinical evaluation. After several regional transplant centers declined the lungs due to their marginal function, clinical teams from Indiana Donor Network, XVIVO and Perfusion Solution went to work.
B-ROLL VIDEO
Time to preserve marginal lungs recovered for donation outside the body and extend the opportunity to assess them and increase their viability for transplantation is now possible at Indiana Donor Network by mechanical perfusion performed by Perfusion Solutions clinicians and implementation of XVIVO’s XPS™ Ex Vivo Lung Perfusion (EVLP) platform.
Indiana Donor Network led the clinical evaluation of the lungs. XVIVO activated its XPS Ex-Vivo Lung Perfusion (EVLP) platform, which extended lung assessment and preservation time and increased the viability of the lungs outside the body for transplant. Perfusion Solution provided lung recovery perfusion equipment, clinical services, staffing, education and ongoing training.
HIGH-RESOLUTION PHOTOS
Photo courtesy of XVIVO.
Recovered lungs are prepared for mechanical perfusion in preparation for testing their function.
Photo courtesy of XVIVO.
Donated lungs await activation of XVIVO’s XPS™ Ex Vivo Lung Perfusion (EVLP) platform.
Photo courtesy of XVIVO.
Perfusion Solutions clinicians work to perfuse a recovered lung donation ahead of assessment.
Once Perfusion Solution identified the lungs as candidates for EVLP, real-time data analysis of lung functionality guided perfusionists and clinical staff through the EVLP protocol, which provided perfusion for nearly five hours. EVLP significantly improved lung functionality.
Following the EVLP process, Indiana Donor Network secured a transplant center to accept the lungs, which were successfully transplanted to save an Indiana man’s life.
“Our collaboration with Perfusion Solution and Indiana Donor Network enabled a successful lung transplant, representing the first of many more lifesaving lung transplants that will be made possible through our EVLP model,” said XVIVO CEO Christoffer Rosenblad. “At XVIVO, we are driven by our vision that nobody should die waiting for a new organ. Strategic partnerships like this are crucial in making that vision a reality.”
Christoffer Rosenblad
CEO
XVIVO
ABOUT MACHINE PERFUSION
Machine perfusion is a controlled process that simulates functionality of an organ outside the body, provides consistent oxygen and nutrients that stabilize a recovered organ, keep it functioning and preserves its health, function and viability for successful transplantation.
Clinical teams have more time to assess a donor organ and even improve organ functionality prior to transplant when machine perfusion is utilized. Perfusion also makes it possible for surgeons to accept an organ for transplant that might otherwise be rejected due to diminished functionality. Additional time provided through perfusion also increases the distance a donor organ can travel for transplant and the geographical reach of organ donation, which both ultimately lead to saving more lives.
“We believe the future of transplantation is driven by strong collaboration and organ procurement organization-led innovation. When OPOs, transplant centers and perfusion specialists operate as one coordinated team, together we honor the gift of donation by maximizing every viable organ,” said Jon Bohannen, executive vice president of sales and clinical integration at Perfusion Solution. “Through disciplined execution and shared clinical governance, we are helping transform marginal opportunities into lifesaving transplants. Collaboration is not just part of our model – it is the engine that allows us to save more lives.”
Jon Bohannen
Vice President of Sales and Clinical Integration
Perfusion Solutions
Donated lungs are perfused using XVIVO’s XPS™ Ex Vivo Lung Perfusion (EVLP) platform. Photo courtesy of XVIVO.
Implementation of the XVIVO and Perfusion Solution partnership is the latest way Indiana Donor Network is utilizing advanced machine perfusion technologies to keep organ donations animated and maintain their viability from recovery to transplant. Kidney and liver perfusion devices are also in use to keep those organs healthy, vibrant, nourished and animated while increasing time for clinical assessment and transport to awaiting recipients spanning more geographic locations within the U.S.
CONTACT
Duane Brodt
dbrodt@INDonorNetwork.org
O: 317.222.3437 | C: 317.675.0288
MEDIA ASSETS
Websites
Indiana Donor Network
Donate Life Indiana
Resources
Quick Facts about Organ Donation and Transplantation
Facts about Tissue Donation
About Donate Life Indiana
Indiana Transplant Hospitals
IU Health
Ascension St. Vincent
SOCIAL CHANNELS
National Affiliations
Donate Life America
ABOUT INDIANA DONOR NETWORK
The decision to become an organ, tissue and eye donor is a decision to give the gift of life. Indiana Donor Network serves as the vital link between donors and patients waiting for lifesaving organ transplants, healing tissue and corneas to restore sight. The organization is a federally designated organ recovery organization and accredited tissue bank serving 85 of Indiana’s 92 counties. Its team of nearly 400 dedicated professionals is committed to saving and healing lives through donation and transplantation, championing the cause through education and outreach and supporting donor families in their time of need. For more or to sign up as a donor, visit Indiana Donor Network online.
ABOUT XVIVO
Founded in 1998, XVIVO is dedicated to extending the life of all major organs – so transplant teams around the world can save more lives. Our solutions allow leading clinicians and researchers to push the boundaries of transplantation medicine. XVIVO is headquartered in Gothenburg, Sweden, and has offices and research sites on two continents. The company is listed on Nasdaq Stockholm under the ticker symbol XVIVO. For more, visit XVIVO online.
ABOUT PERFUSION SOLUTION
Perfusion Solution was established in 2007 and is the fastest growing perfusion service provider in the U.S. Over the past 19 years, the company has expanded to offer cutting-edge and cost-effective solutions to its partner hospitals and organ recovery services for organ procurement organizations and transplant center nationwide. The mission of Perfusion Solution is to provide its affiliated hospitals and industry partners with superior quality clinical services, education and product representation. For more, visit Perfusion Solution online.
